Resiquimod
Data Sheet
For research use only. Not for human use.
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| CAS No. | 144875-48-9 | Cat. No. | BCP09103 |
| Name | Resiquimod | ||
| Synonyms | R-848;R848;R 848; S 28463; S-28463; S28463; VML-600; VML600; VML 600; | ||
| SMILES | CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N | ||
| Chemical Name | |||
| Formula | C17H22N4O2 | M. Wt | 314.39 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Resiquimod is a low-molecular-weight immune response modifier. It is reported to possess anti-tumor and anti-viral properties. It has been shown to mimic pathogen associated molecular patterns, activating immune cells through TLR7 and TLR8 (Toll-like receptors 7 and 8). It can induce interferon-alpha sythesis as well as the synthesis of other cytokines in various cell types. Evidence suggests its efficacy again herpes simples virus (HSV) type 2 in vivo. It has been shown to up-regulate IFN-γ production and proliferation by memory CD4+ T cells. It has also been shown to mimic CD40-induced B cell activation. R-848 is an activator of TLR7 and TLR8. | ||
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