CYM 5520
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1449747-00-5 | Cat. No. | BCP24849 |
| Name | CYM 5520 | ||
| Synonyms | CYM-5520; CYM5520; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C21H19N3O2 | M. Wt | 345.4 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | CYM5520 is a pyrrolyl ketone derivative that acts as a potent, selective, allosteric agonist of sphingosine-1-phosphate receptor 2 (S1PR2; EC50 = 480 nM) that does not replace native ligand and its binding is not competitive with JTE-013. The compound CYM-5520 does not show any agonsit activity towards S1PR1, S1PR3, S1PR4 or S1PR5. It acts as a full agonist for both wild type and triple mutant S1PR2 (EC50 = 1.6 and 1.5 µM, respectively). | ||
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