HUHS015
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CAS No. | 1453097-13-6 | Cat. No. | BCP17521 |
Name | HUHS015 | ||
Synonyms | HUHS-015;HUHS 015; | ||
SMILES | OC1=C(CC2=CC=CC=C2)C(C)=NN1C3=NC4=CC=C(C)C=C4N3 | ||
Chemical Name | |||
Formula | C19H18N4O | M. Wt | 318.37 |
Purity | 98% | Storage | Store at 4-8°C |
Description | HUHS015 is a potent PCA-1/ALKBH3 inhibitor both in vitro and in vivo. The bioavailability (BA) of HUHS015 was 7.2% in rats after oral administration. As expected, continuously administering HUHS015 significantly suppressed the growth of DU145 cells, which are human hormone-independent prostate cancer cells, in a mouse xenograft model without untoward effects. |
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