LDC-3140
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CAS No. | 1453833-30-1 | Cat. No. | BCP25189 |
Name | LDC-3140 | ||
Synonyms | LDC3140; LDC 3140; LDC043140; | ||
SMILES | |||
Chemical Name | |||
Formula | C23H33N7O | M. Wt | 423.57 |
Purity | 98% | Storage | Store at 4-8°C |
Description | LDC3140, also known as LDC043140, is a potent CDK7 inhibitor. Cyclin-dependent kinase 7 (CDK7) activates cell cycle CDKs and is a member of the general transcription factor TFIIH. Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells. |
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