Cidofovir dihydrate New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 149394-66-1 | Cat. No. | BCP07716 |
| Name | Cidofovir dihydrate | ||
| Synonyms | Cidofovir hydrate (1:2);Gs-0504;HPMPC dihydrate; (S)-HPMPC dihydrate; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C8H14N3O6P.2(H2O) | M. Wt | 315.22 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Cidofovir dihydrate is the dihydrate of the anhydrous form of cidofovir. Cidofovir is a synthetic, acyclic, monophosphate nucleotide analog of deoxycytidine with antiviral activity, and mostly used against cytomegalovirus (CMV). After incorporation into the host cell, cidofovir is phosphorylated by pyruvate kinases to its active metabolite cidofovir diphosphate. Cidofovir diphosphate, bearing structural similarity to nucleotides, competes with deoxycytosine-5-triphosphate (dCTP) for viral DNA polymerase and gets incorporated into the growing viral DNA strands. As a result, it prevents further DNA polymerization and disrupts DNA replication of viruses. | ||
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