Photochlor
Data Sheet
For research use only. Not for human use.
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| CAS No. | 149402-51-7 | Cat. No. | BCP08986 |
| Name | Photochlor | ||
| Synonyms | HPPH; | ||
| SMILES | CCCCCCOC(C)C1=C2C=C3C(=C(C(=CC4=NC5=C(CC(=O)C5=C4C)C6=NC(=CC(=C1C)N2)C(C6CCC(=O)O)C)N3)CC)C | ||
| Chemical Name | |||
| Formula | C39H48N4O4 | M. Wt | 636.82 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Photochlor (HTTP) is a lipophilic, second-generation, chlorin-based photosensitizer. Upon intravenous administration, HPPH selectively accumulates in the cytoplasm of cancer or pre-cancerous cells. When laser light is applied, a photodynamic reaction between HPPH and oxygen occurs, resulting in the production of cytotoxic free radicals and singlet oxygen and free radical-mediated cell death. Compared to the first-generation photosensitizer porfimer sodium, HPPH shows improved pharmacokinetic properties and causes only mild skin photosensitivity which declines rapidly within a few days after administration. | ||
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