ZA7371
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CAS No. | 1494675-86-3 | Cat. No. | BCP16818 |
Name | ZA7371 | ||
Synonyms | ZA-7371;ZA 7371 TBA-7371; | ||
SMILES | |||
Chemical Name | |||
Formula | C18H21N5O3 | M. Wt | 355.39 |
Purity | 98% | Storage | Store at 4-8°C |
Description | AZ 7371 is a non-covalent inhibitor of decaprenylphosphoryl-β-D-ribose 2’-epimerase (DprE1) with an IC50 value of 10 nM.It also inhibits PDE6 with an IC50 value of 4 μM.AZ 7371 has been shown to be active against M. tuberculosis with an MIC range of 0.78-3.12 μM and demonstrates efficacy in a rodent model of tuberculosis. |
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