IB-MECA
Data Sheet
For research use only. Not for human use.
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| CAS No. | 152918-18-8 | Cat. No. | BCP09014 |
| Name | IB-MECA | ||
| Synonyms | CF101; CF-101; CF 101; ALB-7208; ALB 7208; ALB7208; IB MECA; Piclidenoson; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C18H19IN6O4 | M. Wt | 510.29 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | IB-MECA, also known as CF101, is a specific agonist to the A3 adenosine receptor, which inhibits the development of colon carcinoma growth in cell cultures and xenograft murine models. CF101 has been shown to downregulate PKB/Akt and NF-κB protein expression level. CF101 potentiates the cytotoxic effect of 5-FU, thus preventing drug resistance. The myeloprotective effect of CF101 suggests its development as an add-on treatment to 5-FU. | ||
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