LG100268 New
Data Sheet
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| CAS No. | 153559-76-3 | Cat. No. | BCP08283 |
| Name | LG100268 | ||
| Synonyms | LG 100268 ; LG-100268; | ||
| SMILES | CC1=C(C=C2C(=C1)C(CCC2(C)C)(C)C)C3(CC3)C4=NC=C(C=C4)C(=O)O | ||
| Chemical Name | |||
| Formula | C24H29NO2 | M. Wt | 363.49 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | LG100268 is a potent and selective retinoid X receptor (RXR) agonist (EC50 = 4 nM). Displays >1000-fold selectivity for RXR over RAR. Activates RXR homodimers to induce transcriptional activation. Induces tissue transglutaminase (TGase) activity in HL-60 human promyelocytic leukemia cell line. Also activates RXR/PPARγ heterodimers. | ||
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