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Efavirenz Chemical Structure

Efavirenz

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP27719CAS No. ：154598-52-4Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 154598-52-4 Cat. No. BCP27719
Name Efavirenz
Synonyms Sustiva; Stocrin;DMP 266;DMP-266;DMP266;MDP-266;MDP 266;MDP266;L-743726;L743726;L 743726;
SMILES
Chemical Name
Formula C14H9ClF3NO2 M. Wt 315.67
Purity 98% Storage Store at 4-8°C
Description Efavirenz is a potent inhibitor of the wild-type HIV-1 RT (Ki=2.93 nM) and exhibits IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.Efavirenz is a non-nucleoside reverse transcriptase inhibitor, NNRTI. Efavirenz is highly specific and potent allosteric inhibitors of HIV-1 reverse transcriptase. Efavirenz also inhibits the late stages of HIV-1 replication by interfering with HIV-1 Gag-Pol polyprotein processing. It is used as part of highly active antiretroviral therapy for the treatment of a human immunodeficiency virus type 1.
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HPLC H-NMR
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