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MC-Val-Cit-PABC Chemical Structure

MC-Val-Cit-PABC

Data Sheet For research use only. Not for human use.
Cat. No. :BCP10424CAS No. :159857-81-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 159857-81-5 Cat. No. BCP10424
Name MC-Val-Cit-PABC
Synonyms Mc-Val-Cit-PABC-PNP;MC-VC-PAB-PNP;MC-VAL-CIT-PAB-PNB;MC-Val-Cit-PAB-PNP;CS-1816;CS1816;
SMILES
Chemical Name
Formula C35H43N7O11 M. Wt 737.76
Purity 98% Storage Store at 4-8°C
Description MC-Val-Cit-PAB-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a promising stance in the delivery of therapeutic agents by providing distinct advantage of improving therapeutic potential of drugs. Use of specialized linkers makes them unique in their in vivo therapeutic application by providing target tissue-specific release of drug
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