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NIBR189 Chemical Structure

NIBR189

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP16145CAS No. ：1599432-08-2Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1599432-08-2 Cat. No. BCP16145
Name NIBR189
Synonyms NIBR-189;NIBR 189;
SMILES
Chemical Name
Formula C21H21BrN2O3 M. Wt 429.31
Purity 98% Storage Store at 4-8°C
Description NIBR-189 is a potent and selective EBI2 (GPR183) receptor antagonist (IC50 values are 11 and 15 nM for human and mouse EBI2 receptors respectively). NIBR-189 blocks migration of a monocyte cell line called U937, suggesting a functional role of the oxysterol/EBI2 pathway in these immune cells.
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