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CAS No. | 160800-57-7 | Cat. No. | BCP24782 |
Name | Auristatin E | ||
Synonyms | |||
SMILES | CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C | ||
Chemical Name | |||
Formula | C40H69N5O7 | M. Wt | 732.01 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; it is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent that inhibits tubulin polymerization. Auristatin E-antibody conjugates have proven to be successful anticancer agents. |
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