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Auristatin E Chemical Structure

Auristatin E

Data Sheet For research use only. Not for human use.
Cat. No. :BCP24782CAS No. :160800-57-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 160800-57-7 Cat. No. BCP24782
Name Auristatin E
Synonyms
SMILES CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C
Chemical Name
Formula C40H69N5O7 M. Wt 732.01
Purity 98% Storage Store at 4-8°C
Description Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; it is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent that inhibits tubulin polymerization. Auristatin E-antibody conjugates have proven to be successful anticancer agents.
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