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HTH-01-015
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CAS No. | 1613724-42-7 | Cat. No. | BCP14400 |
Name | HTH-01-015 | ||
Synonyms | HTH 01 015; | ||
SMILES | |||
Chemical Name | |||
Formula | C26H28N8O | M. Wt | 468.55 |
Purity | 98% | Storage | Store at 4-8°C |
Description | HTH-01-015 did not markedly suppress the activity of any of the other 139 protein kinases evaluated. Treatment of cells with 10 μM HTH-01-015, the NUAK1 isoform selective inhibitor, only led to a partial inhibition of MYPT1 phosphorylation. In HEK-293 cells expressing wild-type NUAK1, concentrations of 3–10 μM WZ4003 or HTH-01-015 markedly suppressed phosphorylation of MYPT1. |
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