Amentoflavone

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP13255CAS No. ：1617-53-4Purity：98%

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Chemical Properties&Biological Activity

CAS No.	1617-53-4	Cat. No.	BCP13255
Name	Amentoflavone
Synonyms
SMILES
Chemical Name
Formula	C30H18O10	M. Wt	538.46
Purity	98%	Storage	Store at 4-8°C
Description	The compound has been observed to inhibit the expression of INOS, LPS-induced activation of NF?B p50 (NF-κ B), translocation of p65 by LPS and block IKKα(I-κ B α) degradation in macrophages. Amentoflavone has been shown to up-regulate PPAR-γ and block the induction of COX-2. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site. The compound has demonstrated anti-viral activity against respiratory syncytial virus (RSV), with an IC50 of 5.5 μg/ml. Amentoflavone has also pronounced inhibition at an IC50 = 14.9 +/- 1.9 nM of benzodiazepine binding in vitro.

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