Rasagiline mesylate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 161735-79-1 | Cat. No. | BCP05224 |
| Related Products | 136236-51-6（Rasagiline） | ||
| Name | Rasagiline mesylate | ||
| Synonyms | AGN1135; TVP1012;AGN-1135; TVP-1012;AGN 1135; TVP 1012; | ||
| SMILES | CS(=O)(=O)O.C#CCNC1CCC2=CC=CC=C12 | ||
| Chemical Name | |||
| Formula | C13H17NO3S | M. Wt | 267.34 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Rasagiline (N-propargyl-1-(R)-aminoindan) is a novel, highly potent irreversible monoamine oxidase (MAO)-B inhibitor, anti-Parkinsonian drug. Rasagiline is effective as monotherapy or adjunct to L-Dopa for patients with early and late Parkinson's disease (PD) . Rasagiline inhibits MAO-B more potently than selegiline and has the advantage of once-daily dosing. In several large, randomized, placebo-controlled trials, rasagiline has demonstrated efficacy as monotherapy in early PD and as adjunctive therapy in advanced PD. In addition, rasagiline has been shown to have neuroprotective effects in in vitro and in vivo studies. The recently completed delayed-start ADAGIO (Attenuation of Disease Progression with Azilect Given Once-daily) trial suggests a potential disease-modifying effect for rasagiline 1 mg/day, though the clinical import of this finding has yet to be established . | ||
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