GSK481
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1622849-58-4 | Cat. No. | BCP17262 |
| Name | GSK481 | ||
| Synonyms | GSK-481;GSK 481; | ||
| SMILES | O=C(C1=NOC(CC2=CC=CC=C2)=C1)N[C@]3COC4=CC=CC=C4N(C)C3=O | ||
| Chemical Name | |||
| Formula | C21H19N3O4 | M. Wt | 377.39 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GSK481 is a Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitor (RIP1 inhibitor). The recent discovery of the role of receptor interacting protein 1 (RIP1) kinase in tumor necrosis factor (TNF)-mediated inflammation has led to its emergence as a highly promising target for the treatment of multiple inflammatory diseases. | ||
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