Naproxcinod
Data Sheet
For research use only. Not for human use.
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| CAS No. | 163133-43-5 | Cat. No. | BCP08710 |
| Name | Naproxcinod | ||
| Synonyms | Naproxen-N-butyl nitrate; Nitronaproxen; AZD 3582; AZD-3582; AZD3582; HCT3012; HCT-3012; HCT 3012; AR-P-900758XX; NO-naproxen; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C18H21NO6 | M. Wt | 347.36 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Naproxcinod is a nitric oxide-releasing NSAID derivative. Naproxcinod significantly ameliorated skeletal muscle force and resistance to fatigue in sedentary as well as in exercised mice, reduced inflammatory infiltrates and fibrosis deposition in both cardiac and diaphragm muscles. Conversely, the equimolar dose of naproxen showed no effects on fibrosis and improved muscle function only in sedentary mice. In addition to anti-inflammatory activity, naproxcinod as a promising candidate for treatment of Duchenne Muscular Dystrophy. | ||
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