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Flibanserin Chemical Structure

Flibanserin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02131CAS No. :167933-07-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 167933-07-5 Cat. No. BCP02131
Name Flibanserin
Synonyms BIMT-17;BIMT 17;BIMT 17; BIMT 17BS; BIMT-17BS; BIMT17BS; EBD6396; EBD 6396; EBD-6396;
SMILES
Chemical Name
Formula C20H21F3N4O M. Wt 390.4
Purity 98% Storage Store at 4-8°C
Description Flibanserin is a full agonist of the 5-HT1A receptor (Ki = 1 nM) and, with lower affinity, as an antagonist of the 5-HT2A receptor (Ki = 49 nM) and antagonist or very weak partial agonist of the D4 receptor (Ki = 4–24 nM). Despite the much greater affinity of flibanserin for the 5-HT1A receptor, and for reasons that are unknown, flibanserin occupies the 5-HT1A and 5-HT2A receptors in vivo with similar percentages. Flibanserin also has low affinity for the 5-HT2B receptor (Ki = 89.3 nM) and the 5-HT2C receptor (Ki = 88.3 nM), both of which it behaves as an antagonist of.
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