Eganelisib
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1693758-51-8 | Cat. No. | BCP18992 |
| Name | Eganelisib | ||
| Synonyms | IPI549 ;IPI 549;IPI-549; | ||
| SMILES | CC(C1=CC2=C(C(=CC=C2)C#CC3=CN(N=C3)C)C(=O)N1C4=CC=CC=C4)NC(=O)C5=C6N=CC=CN6N=C5N | ||
| Chemical Name | |||
| Formula | C30H24N8O2 | M. Wt | 528.58 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | IPI-549 is a potent and selective phosphoinositide-3-kinase (PI3Kγ) Inhibitor as an Immuno-Oncology Clinical Candidate (Kd = 0.29 nM). Bioactivity data of IPI-549: biochemcial IC50 (nM) for PI3K isoform: 3200 (α); 3500 (β); 16 (γ); and >8400 (δ) respectively. Cellar IC50 (nM) of IPI549 for PI3K isoform: 250 (α); 240 (β); 1.6 (γ); and 180 (δ) respectively. IPI-549 shows >100-fold selectivity over other lipid and protein kinases. IPI-549 demonstrates favorable pharmacokinetic properties and robust inhibition of PI3K-γ mediated neutrophil migration in vivo and is currently in Phase 1 clinical evaluation in subjects with advanced solid tumors. | ||
Recommend Products
More >
-
-
PI3K/mTOR Inhibitor-2
Cat. No.：BCP48401
No.：1848242-58-9
Product Details -
-
Disitertide
Cat. No.：BCP46789
No.：272105-42-7
Product Details -
IHMT-PI3Kδ-372
Cat. No.：BCP46775
No.：2429889-62-1
Product Details -
Gilmelisib
Cat. No.：BCP46378
No.：1845777-61-8
Product Details -
-
ETP-45658
Cat. No.：BCP45165
No.：1198357-79-7
Product Details -
-
Panulisib
Cat. No.：BCP44105
No.：1356033-60-7
Product Details -
Parsaclisib hydrochloride
Cat. No.：BCP42656
No.：1995889-48-9
Product Details -
-
-
-
Nemiralisib
Cat. No.：BCP38658
No.：1254036-71-9
Product Details -
TGR1202 racemate
Cat. No.：BCP24685
No.：1532533-65-5
Product Details -
Umbralisib tosylate
Cat. No.：BCP24684
No.：1532533-72-4
Product Details -
Umbralisib R-enantiomer
Cat. No.：BCP24683
No.：1532533-69-9
Product Details -
Umbralisib sulfate
Cat. No.：BCP24681
No.：1532533-75-7
Product Details -
GSK2292767
Cat. No.：BCP24323
No.：1254036-66-2
Product Details
Tags:Eganelisib supplier,Eganelisib purchase,Eganelisib manufacturer,Eganelisib distributor,Eganelisib cost,Eganelisib buy,Eganelisib for sale