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GSK8573 Chemical Structure

GSK8573

Data Sheet For research use only. Not for human use.
Cat. No. :BCP16859CAS No. :1693766-04-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1693766-04-9 Cat. No. BCP16859
Name GSK8573
Synonyms GSK-8573;GSK 8573;
SMILES CCCOC1=CC2=C(C=C(N2C=C1)C(=O)C)C3=CC(=CC=C3)OC
Chemical Name
Formula C20H21NO3 M. Wt 323.39
Purity 98% Storage Store at 4-8°C
Description GSK-8573 is the inactive control of GSK-2801.GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a family of ubiquitously expressed bromodomain containing proteins. Proteins of the BAZ family are characterized by a carboxy-terminal bromodomain adjacent to a PHD finger and a WACZ motif. In addition four other conserved motifs are typically found in the N-terminus of BAZ family members, namely the LH motif (a leucine-rich helical domain), the ZB2 motif and the BAZ 1 and BAZ 2 motifs. Little is known about the biological function of BAZ2B but it has been suggested to regulate nucleosome mobilization by the ATP-dependent chromatin remodeling factor ISWI.
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