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CAS No. | 1693766-04-9 | Cat. No. | BCP16859 |
Name | GSK8573 | ||
Synonyms | GSK-8573;GSK 8573; | ||
SMILES | CCCOC1=CC2=C(C=C(N2C=C1)C(=O)C)C3=CC(=CC=C3)OC | ||
Chemical Name | |||
Formula | C20H21NO3 | M. Wt | 323.39 |
Purity | 98% | Storage | Store at 4-8°C |
Description | GSK-8573 is the inactive control of GSK-2801.GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a family of ubiquitously expressed bromodomain containing proteins. Proteins of the BAZ family are characterized by a carboxy-terminal bromodomain adjacent to a PHD finger and a WACZ motif. In addition four other conserved motifs are typically found in the N-terminus of BAZ family members, namely the LH motif (a leucine-rich helical domain), the ZB2 motif and the BAZ 1 and BAZ 2 motifs. Little is known about the biological function of BAZ2B but it has been suggested to regulate nucleosome mobilization by the ATP-dependent chromatin remodeling factor ISWI. |
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