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H3B-6527 Chemical Structure

H3B-6527

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP17555CAS No. ：1702259-66-2Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1702259-66-2 Cat. No. BCP17555
Name H3B-6527
Synonyms H3B 6527;H3B6527;Eisai;H3 Biomedicine;
SMILES C=CC(NC1=CC(N2CCN(CC)CC2)=CC=C1NC3=NC=NC(N(C(NC4=C(Cl)C(OC)=CC(OC)=C4Cl)=O)C)=C3)=O
Chemical Name
Formula C29H34Cl2N8O4 M. Wt 629.54
Purity 98% Storage Store at 4-8°C
Description H3B-6527 is a potent and orally active FGFR4 inhibitor with potential antineoplastic activity. Upon administration, H3B-6527 specifically binds to and blocks FGFR4. This prevents the activation of FGFR4, inhibits FGFR4-mediated signaling and leads to an inhibition of cell proliferation in FGFR4-overexpressing tumor cells.
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H-NMR
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