Dalbavancin
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CAS No. | 171500-79-1 | Cat. No. | BCP04495 |
Name | Dalbavancin | ||
Synonyms | Dalvance;MDL-63397;MDL 63397;MDL63397;BI-397;BI 397;BI397; | ||
SMILES | |||
Chemical Name | |||
Formula | C88H100Cl2N10O28 | M. Wt | 1816.71 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Dalbavancin demonstrated potent in vitro activity against B. anthracis (MIC range, < or =0.03 to 0.5 mg/liter; MIC(50) and MIC(90), 0.06 and 0.25 mg/liter, respectively), which led us to test its efficacy in a murine inhalation anthrax model. At 20 mg/kg, the dalbavancin activity was detectable for 6 days after administration (terminal half-life, 53 h), indicating that long intervals between doses were feasible. |
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