Sildenafil citrate
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 171599-83-0 | Cat. No. | BCP02960 |
| Name | Sildenafil citrate | ||
| Synonyms | Viagra;Revatio; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C28H38N6O11S | M. Wt | 666.7 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Sildenafil citrate is a potent PDE type 5 reversible and selective inhibitor that blocks cGMP hydrolysis effectively (Ki ～3 nM). Sildenafil exhibited high affinity for PDE type 5 and type 6 with inhibition constants (Ki) of ～3.5 and 33 nM, respectively. Sildenafil enhances sodium nitroprusside- or transmural electrical stimulation-induced relaxation of precontracted corpus cavernosum muscle strips in organ baths, suggesting that sildenafil augments the activity of NO-mediated relaxation. Sildenafil citrate increases intracellular cGMP concentrations in cultured smooth muscle cells treated with sodium nitroprusside and in rabbit corpus cavernosum in vitro. Sildenafil is metabolized in the liver by cytochrome P450 and is converted into an active metabolite with characteristics similar to the parent compound. | ||
Recommend Products
More >
-
-
Enpp-1-IN-14
Cat. No.：BCP47912
No.：2687222-59-7
Product Details -
-
Mirodenafil dihydrochloride
Cat. No.：BCP46802
No.：862189-96-6
Product Details -
BAY 2666605
Cat. No.：BCP45964
No.：2275774-60-0
Product Details -
Tetomilast
Cat. No.：BCP45927
No.：145739-56-6
Product Details -
Orismilast
Cat. No.：BCP45468
No.：1353546-86-7
Product Details -
Tovinontrine
Cat. No.：BCP44778
No.：2062661-53-2
Product Details -
Lenrispodun phosphate
Cat. No.：BCP44187
No.：1642303-38-5
Product Details -
-
-
-
ATX inhibitor 1
Cat. No.：BCP37626
No.：2225892-70-4
Product Details -
-
-
Mardepodect hydrochloride
Cat. No.：BCP35070
No.：2070014-78-5
Product Details -
DSR-141562
Cat. No.：BCP34050
No.：2007975-22-4
Product Details -
-
BIO-32546
Cat. No.：BCP28835
No.：1548743-66-3
Product Details -
Tags:Sildenafil citrate supplier,Sildenafil citrate purchase,Sildenafil citrate manufacturer,Sildenafil citrate distributor,Sildenafil citrate cost,Sildenafil citrate buy,Sildenafil citrate for sale