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AN-2718 Chemical Structure

AN-2718

Data Sheet For research use only. Not for human use.
Cat. No. :BCP16819CAS No. :174672-06-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 174672-06-1 Cat. No. BCP16819
Name AN-2718
Synonyms AN 2718;AN2718;
SMILES OB1OCC2=CC(Cl)=CC=C21
Chemical Name
Formula C7H6BClO2 M. Wt 168.39
Purity 98% Storage Store at 4-8°C
Description AN2718 is a novel boron-containing small molecule that inhibits an essential protein synthesis enzyme, leucyl-transfer RNA synthetase, or LeuRS. This enzyme plays an essential role in fungal protein synthesis by attaching the leucine amino acid to transfer RNA, or tRNA. AN2718, an investigational topical anti-fungal product candidate for the potential treatment of skin and nail infections. At various concentrations, AN2718 gel showed low irritation potential, leading investigators to conclude that application site reactions in future efficacy trials would be unlikely.
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