Sarizotan 2HCl salt New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 177976-12-4 | Cat. No. | BCP18870 |
| Name | Sarizotan 2HCl salt | ||
| Synonyms | Sarizotan dihydrochloride; | ||
| SMILES | C1CC2=CC=CC=C2OC1CNCC3=CN=CC(=C3)C4=CC=C(C=C4)F.Cl.Cl | ||
| Chemical Name | |||
| Formula | C22H23Cl2FN2O | M. Wt | 421.34 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Sarizotan, also known as EMD-128130, is a Dopamine D2 receptor partial agonist and Serotonin 1A receptor agonist. Sarizotan exhibits affinity at serotonin and dopamine receptors. Sarizotan effectively suppresses levodopa-induced dyskinesia in primate and rodent models of Parkinson's disease, and tardive dyskinesia in a rodent model. Sarizotan is a full agonist at D3 and D4.4 receptors (EC50=5.6 and 5.4 nM, respectively) but a partial agonist at D2S, D2L and D4.2 receptors (EC50=29, 23 and 4.5 nM, respectively). Sarizotan is an antagonist at D2S and D2L receptors (IC50=52 and 121 nM, respectively). Sarizotan is a full agonist at D2L, D3, D4.2 and D4.4 receptors (EC50=0.51, 0.47, 0.48 and 0.23 nM, respectively) but a partial agonist at D2S receptors (EC50=0.6 nM). | ||
Recommend Products
More >
-
Pipamperone dihydrochloride
Cat. No.：BCP49191
No.：2448-68-2
Product Details -
NAS-181 methanesulfonate
Cat. No.：BCP49052
No.：205242-62-2
Product Details -
Opiranserin
Cat. No.：BCP48961
No.：1441000-45-8
Product Details -
-
Prucalopride hydrochloride
Cat. No.：BCP48408
No.：179474-80-7
Product Details -
-
(Z)-Thiothixene
Cat. No.：BCP48214
No.：3313-26-6
Product Details -
S14506 hydrochloride
Cat. No.：BCP48185
No.：286369-38-8
Product Details -
-
-
Imipramine Hydrochloride
Cat. No.：BCP46885
No.：113-52-0
Product Details -
Zacopride hydrochloride
Cat. No.：BCP46391
No.：101303-98-4
Product Details -
-
-
PF-4479745
Cat. No.：BCP45867
No.：1065110-43-1
Product Details -
PF-3246799 hydrochloride
Cat. No.：BCP45866
No.：1065114-52-4
Product Details -
-
DOI hydrochloride
Cat. No.：BCP25643
No.：42203-78-1
Product Details -
-
Temanogrel
Cat. No.：BCP24269
No.：887936-68-7
Product Details
Tags:Sarizotan 2HCl salt supplier,Sarizotan 2HCl salt purchase,Sarizotan 2HCl salt manufacturer,Sarizotan 2HCl salt distributor,Sarizotan 2HCl salt cost,Sarizotan 2HCl salt buy,Sarizotan 2HCl salt for sale