RN-1
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1781835-13-9 | Cat. No. | BCP20812 |
| Name | RN-1 | ||
| Synonyms | RN-1 Dihydrochloride; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C23H29N3O2 | M. Wt | 452.42 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Lysine-specific demethylase 1 (LSD1) belongs to the family of flavin adenine dinucleotide (FAD)-dependent amine oxidases that include monoamine oxidases (MAOs). RN-1 is a potent, irreversible inhibitor of LSD1 (IC50 = 70 nM).2 It is much less effective against MAO-A and MAO-B (IC50s = 0.51 and 2.8 μM, respectively).2 Following intraperitoneal administration, RN-1 penetrates the blood-brain barrier and distributes in mice to a brain/plasma exposure ratio of 88.9. It blocks long-term but not short-term memory in mice.2 RN-1 also induces cytotoxicity in ovarian cancer cell lines and induces fetal hemoglobin synthesis while reducing disease pathology in sickle cell mice. | ||
Recommend Products
More >
-
(2S)-2-hydroxypentanedioic acid
Cat. No.：BCP47205
No.：13095-48-2
Product Details -
-
Bomedemstat
Cat. No.：BCP45548
No.：1990504-34-1
Product Details -
-
KDM2A/7A-IN-1
Cat. No.：BCP44938
No.：2169272-46-0
Product Details -
-
Bomedemstat ditosylate
Cat. No.：BCP44102
No.：1990504-72-7
Product Details -
Pulrodemstat
Cat. No.：BCP44101
No.：1821307-10-1
Product Details -
-
DDP-38003 2HCl
Cat. No.：BCP39854
No.：1831167-98-6
Product Details -
KDM5-IN-1
Cat. No.：BCP37630
No.：1628210-26-3
Product Details -
-
CC-90011 besylate
Cat. No.：BCP33218
No.：2097523-60-7
Product Details -
KDM4D-IN-1
Cat. No.：BCP32624
No.：2098902-68-0
Product Details -
-
-
T-3775440
Cat. No.：BCP30535
No.：1422620-34-5
Product Details -
T-3775440 hydrochloride
Cat. No.：BCP30534
No.：1422535-52-1
Product Details -
-
OG-L002 hydrochloride
Cat. No.：BCP25948
No.：1357298-75-9
Product Details
Tags:RN-1 supplier,RN-1 purchase,RN-1 manufacturer,RN-1 distributor,RN-1 cost,RN-1 buy,RN-1 for sale