1400W
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CAS No. | 180001-34-7 | Cat. No. | BCP24904 |
Related Products | 214358-33-5(1400W Dihydrochloride) | ||
Name | 1400W | ||
Synonyms | N-(3-(aminomethyl)benzyl)acetimidine; | ||
SMILES | CC(NCC1=CC=CC(CN)=C1)=N | ||
Chemical Name | |||
Formula | C10H15N3 | M. Wt | 177.25 |
Purity | 98% | Storage | Store at 4-8°C |
Description | 1400W is a highly selective inducible nitric oxide synthase inhibitor and is a potential disease modifier in the rat kainate model of temporal lobe epilepsy. 1400W reduces ischemia reperfusion injury in an ex-vivo porcine model of the donation after circulatory death kidney donor. 1400W ameliorates acute hypobaric hypoxia/reoxygenation-induced cognitive deficits by suppressing the induction of inducible nitric oxide synthase in rat cerebral cortex microglia. 1400W blocks death pathway of LPS-induced activated-microglia to preOLs. |
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