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SHP099 hydrochloride Chemical Structure

SHP099 hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP18365CAS No. :1801747-11-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1801747-11-4 Cat. No. BCP18365
Name SHP099 hydrochloride
Synonyms SHP-099 hydrochloride;SHP 099 hydrochloride;SHP-099 HCl;
SMILES
Chemical Name
Formula C16H20Cl3N5 M. Wt 388.72
Purity 98% Storage Store at 4-8°C
Description SHP099 exhibits dose-dependent pathway inhibition and antitumor activity in xenograft models. SHP2 is a nonreceptor protein tyrosine phosphatase (PTP) encoded by the PTPN11 gene involved in cell growth and differentiation via the MAPK signaling pathway. SHP2 also purportedly plays an important role in the programmed cell death pathway (PD-1/PD-L1). Because it is an oncoprotein associated with multiple cancer-related diseases, as well as a potential immunomodulator, controlling SHP2 activity is of significant therapeutic interest.
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