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Olmutinib Chemical Structure

Olmutinib

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP16691CAS No. ：1802181-20-9Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1802181-20-9 Cat. No. BCP16691
Name Olmutinib
Synonyms BI-1482694;BI 1482694;BI1482694;HM-61713;HM 61713;HM61713;
SMILES
Chemical Name
Formula C26H26N6O2S M. Wt 486.59
Purity 98% Storage Store at 4-8°C
Description Olmutinib, also known as HM61713 and BI-1482694, is a potent small molecule inhibitor of Bruton's tyrosine kinase (BTK). BTK is a member of the Tec family of non-receptor protein tyrosine kinases. BTK is mostly expressed in hematopoietic cells such as B cells, mast cells and macrophages. BTK plays key roles in multiple cell signaling pathways including B-Cell Receptor (BCR) and Fc receptor (FcR) signaling cascades and is an essential mediator not only in B-cell dependent but also in myeloid cell dependent inflammatory arthritis. HM71224 has been selected as a novel therapeutic agent for the treatment of autoimmune diseases such as RA.
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