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CAS No. | 1807988-02-8 | Cat. No. | BCP20910 |
Related Products | 1611493-60-7(Bictegravir) | ||
Name | Bictegravir Sodium | ||
Synonyms | GS-9883; GS 9883; GS9883; GS-9883-01; GS9883-01; GS 9883-01; | ||
SMILES | C1C[C@@H]2C[C@H]1N3[C@H](O2)CN4C=C(C(=O)C(=C4C3=O)[O-])C(=O)NCC5=C(C=C(C=C5F)F)F.[Na+] | ||
Chemical Name | |||
Formula | C21H17F3N3NaO5 | M. Wt | 471.36 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Bictegravir, also known as GS-9883, is a potent, unboosted, once-Daily HIV-1 Integrase Strand Transfer Inhibitor (INSTI) (IC50 - 1.6 nM) with improved pharmacokinetics and in vitro resistance profile. Bictegravir is currently in Phase 3 trials as part of a single tablet regimen in combination with tenofovir alafenamide (TAF) and emtricitabine (FTC) for the treatment of HIV-1 infection (bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg). |
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