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SGC2085.hcl Chemical Structure

SGC2085.hcl

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP28941CAS No. ：1821908-49-9Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1821908-49-9 Cat. No. BCP28941
Name SGC2085.hcl
Synonyms SGC-2085; SGC 2085;SGC2085 HCl;
SMILES C[C@H](N)C(NCC1=CC=C(OC2=CC(C)=CC(C)=C2)C(C)=C1)=O.[H]Cl
Chemical Name
Formula C19H24N2O2 . HCl M. Wt 348.87
Purity 98% Storage Store at 4-8°C
Description SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor with an IC50 of 50 nM and more than undred-fold selectivity over other PRMTs. CARM1 is an important positive modulator of Wnt/β-catenin transcription and neoplastic transformation in colorectal cancer as well as a critical factor in estrogen-stimulated breast cancer growth, and its depletion results in decreased proliferation of myeloid leukemia cells in vivo.
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