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Tipiracil Chemical Structure

Tipiracil

Data Sheet For research use only. Not for human use.
Cat. No. :BCP24231CAS No. :183204-74-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 183204-74-2 Cat. No. BCP24231
Related Products 183204-72-0(Tipiracil HCl) 733030-01-8(Trifluridine-tipiracil hydrochloride mixture)
Name Tipiracil
Synonyms TAS-1-462; MA-1; TPI;
SMILES
Chemical Name
Formula C9H11ClN4O2 M. Wt 242.66
Purity 98% Storage Store at 4-8°C
Description Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials. TAS-102 consists of the cytotoxin Trifluridine and the thymidine phosphorylase inhibitor (TPI) tipiracil. Trifluridine is incorporated into DNA during DNA synthesis and inhibits tumor cell growth. Tipiracil protects trifluridine from being broken down when taken orally. TAS-102 was approved in Japan in 2015.
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