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OSI420 HCl Chemical Structure

OSI420 HCl

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP28007CAS No. ：183320-51-6Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 183320-51-6 Cat. No. BCP28007
Name OSI420 HCl
Synonyms OSI-420; OSI 420; CP473420; CP-473420; CP 473420; OSI420 HCL;Desmethyl erlotinib;O-Desmethylerlotinib hydrochloride;
SMILES
Chemical Name
Formula C21H21N3O4.HCl M. Wt 415.88
Purity 98% Storage Store at 4-8°C
Description OSI-420 is an active metabolite of erlotinib, which is a potent EGFR tyrosin kinase inhibitor. OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.
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