PD153035 HCl

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP16320CAS No. ：183322-45-4Purity：98%

Get Quotation Now

Tel: 0086-17754423994 or orders@biochempartner.com

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name			* Applicant name
Catalog Number			* Institution/Company
* Email address			Phone number
Country			* Quantity Required
Remarks

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name			* Applicant name
Catalog Number			* Institution/Company
* Email address			Phone number
Country			* Quantity Required
Remarks

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name			* Applicant name
Catalog Number			* Institution/Company
* Email address			Phone number
Country			* Quantity Required
Remarks

Chemical Properties&Biological Activity

CAS No.	183322-45-4	Cat. No.	BCP16320
Name	PD153035 HCl
Synonyms	PD-153035 HCl;PD 153035 HCl;
SMILES
Chemical Name
Formula	C16H14BrN3O2.HCl	M. Wt	396.67
Purity	98%	Storage	Store at 4-8°C
Description	PD153035 is a ATP-competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectively blocks the enhancement of mitogenesis, induction of early gene expression, and oncogenic transformation that occur in response to EGF receptor stimulation. With human fibroblasts and epidermoid carcinoma cells, PD153035 at nanomolar concentrations rapidly inhibits EGFR autophosphorylation. With breast and ovarian cancer cells, PD153035 not only blocks cell growth via inhibition of EGFR, but also upregulates the expression of the tumor suppressor retinoic acid receptor-beta 2 (RAR-beta2).

Quality Control&Technical Support

Recommend Products

More >

Tags:PD153035 HCl supplier,PD153035 HCl purchase,PD153035 HCl manufacturer,PD153035 HCl distributor,PD153035 HCl cost,PD153035 HCl buy,PD153035 HCl for sale

PD153035 HCl

About BioChemPartner

Customer Support

Ordering

Contact BioChemPartner