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Etanercept Chemical Structure

Etanercept

Data Sheet For research use only. Not for human use.
Cat. No. :BCP12862CAS No. :185243-69-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 185243-69-0 Cat. No. BCP12862
Name Etanercept
Synonyms TNFR-Fc fusion protein;
SMILES
Chemical Name
Formula C2224H3475N621O698S36 M. Wt 51234.9
Purity 98% Storage Store at 4-8°C
Description Etanercept is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. The biosimilar is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids and has an apparent molecular weight of approximately 150 kDa.
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