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RS102221 HCl Chemical Structure

RS102221 HCl

Data Sheet For research use only. Not for human use.
Cat. No. :BCP03496CAS No. :185376-97-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 185376-97-0 Cat. No. BCP03496
Name RS102221 HCl
Synonyms RS 102221 HCl;RS-102221 HCl;
SMILES
Chemical Name
Formula C27H32ClF3N4O7S M. Wt 649.08
Purity 98% Storage Store at 4-8°C
Description RS-102221 is a drug developed by Hoffmann–La Roche, which was one of the first compounds discovered that acts as a potent and selective antagonist at the serotonin 5-HT2C receptor, with around 100x selectivity over the closely related 5-HT2A and 5-HT2B receptors. It has anxiolytic effects in animal studies, increases the effectiveness of SSRI antidepressants, and shows a complex interaction with cocaine, increasing some effects but decreasing others, reflecting a role for the 5-HT2C receptor in regulation of the dopamine signalling system in the brain.
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