UNC3866 TFA salt
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1872382-48-3 | Cat. No. | BCP24826 |
| Name | UNC3866 TFA salt | ||
| Synonyms | UNC-3866 TFA salt;UNC3866;UNC-3866;UNC 3866; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C45H67F3N6O10 | M. Wt | 909.06 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | UNC3866 is a potent and selective antagonist of CBX4 and CBX7 chromodomains with (Kd ≈ 100 nM). It is 6- to 63-fold selective for these chromodomains over the other CBX and CDY chromodomains. UNC3866 was also highly selective versus >250 other molecular targets including chromatin regulatory proteins and a general pharmacology panel. UNC3866 was enabled in part by the use of molecular dynamics simulations performed with CBX7 and its endogenous substrate. | ||
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