Darovasertib New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1874276-76-2 | Cat. No. | BCP20781 |
| Name | Darovasertib | ||
| Synonyms | LXS196; LXS-196; LXS 196; IDE196; IDE 196;IDE-196;NVP-LXS196; NVPLXS196; NVP LXS196; | ||
| SMILES | CC1(CCN(CC1)C2=C(N=CC=C2)NC(=O)C3=NC(=CN=C3N)C4=C(C=CC=N4)C(F)(F)F)N | ||
| Chemical Name | |||
| Formula | C22H23F3N8O | M. Wt | 472.48 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | LXS-196 is a potent and orally active protein kinase C inhibitor for the treatment of uveal melanoma. Upon oral administration, protein kinase C inhibitor LXS196 binds to and inhibits PKC, which prevents the activation of PKC-mediated signaling pathways. This may lead to the induction of cell cycle arrest and apoptosis in susceptible tumor cells. PKC, a serine/threonine protein kinase overexpressed in certain types of cancer cells, is involved in tumor cell differentiation, proliferation, invasion and survival. | ||
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