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Streptozocin Chemical Structure

Streptozocin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP08218CAS No. :18883-66-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 18883-66-4 Cat. No. BCP08218
Name Streptozocin
Synonyms U9889; U-9889; U 9889; NCI-C03167; NSC-85998; AI3-50821; NRRL 2697; STZ; SZC; SZN;
SMILES
Chemical Name
Formula C8H15N3O7 M. Wt 265.22
Purity 98% Storage Store at 4-8°C
Description Streptozocin is a methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozocin alkylates DNA, forming inter-strand DNA cross-links and inhibiting DNA synthesis. Due to its glucose moiety, this agent is readily taken up by pancreatic beta cells, inducing diabetes mellitus at high concentrations. Unlike other nitrosoureas, streptozocin causes little myelosuppression.
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