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ABT492 Chemical Structure

ABT492

Data Sheet For research use only. Not for human use.
Cat. No. :BCP21227CAS No. :189279-58-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 189279-58-1 Cat. No. BCP21227
Name ABT492
Synonyms Delafloxacin; Delafloxacinum; ABT-492 ; ABT 492;
SMILES
Chemical Name
Formula C18H12ClF3N4O4 M. Wt 440.76
Purity 98% Storage Store at 4-8°C
Description ABT-492 is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens. It exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows: Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015. It was four- to sixfold more active than other fluoroquinolones, including against levofloxacin-resistant strains of S. pneumoniae, methicillin-resistant Staphylococcus aureus, and Prevotella species.
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