GSK6853
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1910124-24-1 | Cat. No. | BCP18335 |
| Name | GSK6853 | ||
| Synonyms | GSK-6853;GSK 6853; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C22H27N5O3 | M. Wt | 409.48 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhibitor of the BRPF1 bromodomain, and demonstrated properties suitable for cellular and in vivo studies. The BRPF (Bromodomain and PHD Fingercontaining) protein family are important scaffolding proteins for assembly of MYST histone acetyltransferase complexes. BRPF1 (bromodomain and PHD finger containing protein 1) is involved in the epigenetic regulation of gene expression and have been implicated in human cancer. | ||
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