Ezetimibe Ketone New
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CAS No. | 191330-56-0 | Cat. No. | BCP09273 |
Name | Ezetimibe Ketone | ||
Synonyms | Ezetimibe Intermediate-X;EZM-K; | ||
SMILES | C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(=O)C4=CC=C(C=C4)F)O | ||
Chemical Name | |||
Formula | C24H19F2NO3 | M. Wt | 407.41 |
Purity | 99% | Storage | Store at 4-8°C |
Description | Ezetimibe Ketone is Phase-I metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. |
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