Prazosin

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP14556CAS No. ：19216-56-9Purity：98%

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CAS No.	19216-56-9	Cat. No.	BCP14556
Name	Prazosin
Synonyms	Furazosin;Lentopres;
SMILES
Chemical Name
Formula	C19H21N5O4	M. Wt	383.4
Purity	98%	Storage	Store at 4-8°C
Description	Prazosin, is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, andpanic disorder. It is an alpha-adrenergic blocker that is specific for the alpha-1 receptors. These receptors are found on vascular smooth muscle, where they are responsible for the vasoconstrictive action of norepinephrine. They are also found throughout the central nervous system. As of 2013, prazosin is off-patent in the US, and the FDA has approved at least one generic manufacturer.In addition to its alpha-blocking activity, prazosin is an antagonist of the MT3 receptor (which is not present in humans), with selectivity for this receptor over the MT1 and MT2 receptors. Prazosin is orally active and has a minimal effect on cardiac function due to its alpha-1 receptor selectivity. However, when prazosin is initially started, heart rate and contractility go up in order to maintain the pre-treatment blood pressures because the body has reached homeostasis at its abnormally high blood pressure. The