Ximelagatran
Data Sheet
For research use only. Not for human use.
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| CAS No. | 192939-46-1 | Cat. No. | BCP10194 |
| Name | Ximelagatran | ||
| Synonyms | H 376-95; H 376/95; H 37695; H-37695; H37695; Exanta; Exarta; | ||
| SMILES | CCOC(=O)CNC(C1CCCCC1)C(=O)N2CCC2C(=O)NCC3=CC=C(C=C3)C(=NO)N | ||
| Chemical Name | |||
| Formula | C24H35N5O5 | M. Wt | 473.58 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Ximelagatran (Exanta or Exarta, H 376/95) is an anticoagulant that has been investigated extensively as a replacement for warfarin that would overcome the problematic dietary, drug interaction, and monitoring issues associated with warfarin therapy. In 2006, this drug was discontinued due to hepatotoxicity (liver damage). Ximelagatran, a direct thrombin inhibitor,[3] was the first member of this class that can be taken orally. It acts solely by inhibiting the actions of thrombin. It is taken orally twice daily, and rapidly absorbed by the small intestine. Ximelagatran is a prodrug, being converted in vivo to the active agent melagatran. | ||
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