ZM323881 hydrochloride

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP24296CAS No. ：193000-39-4Purity：98%

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Chemical Properties&Biological Activity

CAS No.	193000-39-4	Cat. No.	BCP24296
Name	ZM323881 hydrochloride
Synonyms	ZM323881 HCl;ZM 323881 HCl;ZM-323881 HCl;
SMILES
Chemical Name
Formula	C22H18FN3O2.HCl	M. Wt	411.86
Purity	98%	Storage	Store at 4-8°C
Description	ZM323881 hydrochloride is a potent and selective VEGFR2 inhibitor with an IC50 of less than 2 nM. ZM323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) < 2 nM), compared with other receptor tyrosine kinases, including VEGF-R1 (IC(50) > 50 microM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation (IC(50) = 8 nM) and VEGF-R2 tyrosine phosphorylation in vitro.

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