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CAS No. | 19608-29-8 | Cat. No. | BCP02565 |
Name | Clascoterone | ||
Synonyms | CB-03-01;CB 03-01; CB03-01; Cortexolone 17alpha-propionate;Cortexolone 17α-propionate;17 alpha-propionate;17α-propionate; Cortexolone 17 alpha-propionate; | ||
SMILES | CCC(O[C@]1(C(CO)=O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O | ||
Chemical Name | |||
Formula | C24H34O5 | M. Wt | 402.52 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Clascoterone, also known as CB-03-01 and cortexolone 17alpha-propionate, is a topical and peripherally selective and potent androgen antagonist for topical treatment of acne vulgaris. CB-03-01 1% cream seems to fit with the profile of an ideal antiandrogen for topical use. CB-03-01 is clinically more effective than comparator. Acne vulgaris is a disorder of the pilosebaceous unit in which the androgens contribute to its onset and persistence. The use of antiandrogens is therefore potentially effective. |
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