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Mesna Chemical Structure

Mesna

Data Sheet For research use only. Not for human use.
Cat. No. :BCP14384CAS No. :19767-45-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 19767-45-4 Cat. No. BCP14384
Name Mesna
Synonyms Sodium 2-mercaptoethanesulfonate; Mesnaum; Mesnex;
SMILES
Chemical Name
Formula C2H5NaO3S2 M. Wt 164.18
Purity 98% Storage Store at 4-8°C
Description MESNA had no effect on the qualitative and quantitative characteristics of the indicated processes in both the types of the doxorubicin sensitive cells. The combined use of doxorubicin and phosphamide or cyclophosphane the use of MESNA for lowering the urotoxic action of oxazophosphorines had no effect on the biological efficacy of doxorubicin . in vivo: AMH-positive follicles were significantly decreased after cisplatin administration, which was significantly reversed when mesna was co-administered with cisplatin. The end product of lipid peroxidation, malondialdehyde (MDA), was significantly increased, but the anti-oxidative enzymatic activity of superoxide dismutase (SOD) and glutathione (GSH) were significantly decreased in cisplatin groups when compared with NS group. In contrast, after co-administration of cisplatin with mesna, MDA was significantly decreased whereas the activity of SOD and the concentration of GSH were increased. Moreover, mesna did not decrease the anti-tumor p
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