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Atazanavir Chemical Structure

Atazanavir

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP09735CAS No. ：198904-31-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 198904-31-3 Cat. No. BCP09735
Name Atazanavir
Synonyms BMS 232632;BMS-232632;BMS232632;
SMILES
Chemical Name
Formula C38H52N6O7 M. Wt 704.87
Purity 98% Storage Store at 4-8°C
Description Atazanavir is generally more potent than the five currently approved HIV-1 Prt inhibitors. Atazanavir inhibited the proteolytic cleavage of the viral gag precursor p55 polyprotein in a dose-dependent manner, with a EC50 of approximately 47 nM. Furthermore, Atazanavir is highly selective for HIV-1 Prt and exhibits cytotoxicity only at concentrations 6,500- to 23,000-fold higher than that required for anti-HIV activity. Atazanavir may be an effective HIV-1 inhibitor that may be utilized in a variety of different drug combinations.
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