ITSA-1
Data Sheet
For research use only. Not for human use.
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| CAS No. | 200626-61-5 | Cat. No. | BCP18420 |
| Name | ITSA-1 | ||
| Synonyms | ITSA1;1-(2,4-Dichlorobenzoyl)-1H-benzotriazole; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C13H7Cl2N3O | M. Wt | 292.12 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ITSA1 (N-(1H-Benzotriazol-1-yl)-2,4-dichlorobenzamide) is an HDAC activator via TSA suppression, but shows no activity towards other HDAC inhibitors. TSA (Trichostatin A) is an inhibitor of histone deacetylase. ITSA1 was found to specifically counteract TSA-induced cell cycle arrest, histone acetylation, transcriptional activation, and cytoplasmic alpha-tubulin acetylation. | ||
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